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About Your Infusion

RADICAVA® (edaravone) is an intravenous (IV) medication for the treatment of amyotrophic lateral sclerosis (ALS). This means that RADICAVA® is given through a needle in a vein.

  • RADICAVA® is administered as two 30 mg IV bags
  • It takes about 1 hour to receive a full dose
  • Your healthcare provider (HCP) will tell you how often you will receive RADICAVA®
  • Your HCP will monitor you closely during your ALS treatment

Ready to start your treatment journey with RADICAVA®?

A RADICAVA® Clinical Educator will be here for you to offer educational support and help locate any nearby ALS resources.

Learn more >

The Clinical Educator is an educational resource for patients who have been prescribed RADICAVA®. The Clinical Educator is provided by MTPA and VMS and is not affiliated with or provided by a healthcare provider. The Clinical Educator does not provide medical advice. All questions about your condition, diagnosis, or treatment should be referred to your healthcare provider.

RADICAVA® should be administered under the guidance of an HCP.
You may receive RADICAVA® at:

Doctor's Office'

A doctor's office

Infusion Center

An infusion center

A Hospital

A hospital

Home

Home

Talk to your HCP and your insurance provider to see what options are right for you.

Before you receive RADICAVA®, tell your HCP about all of your medical conditions, including if you:

  • Have asthma
  • Are allergic to other medicines
  • Are pregnant or plan to become pregnant (it is not known if RADICAVA® will harm your unborn baby)
  • Are breastfeeding or plan to breastfeed (it is not known if RADICAVA® passes into your breastmilk; you and your HCP should decide if you will receive RADICAVA® or breastfeed)

Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Infusion schedule

RADICAVA® is an ongoing treatment for ALS. For the first cycle, RADICAVA® is infused for 14 days, followed by a 14-day drug-free period. Subsequent cycles are infused for 10 days within a 14-day period, followed by a 14-day drug-free period.

Searchlight Support® can help you find an infusion site of care. To learn more, call 1-844-SRCHLGT (1-844-772-4548) or go here.


Administering RADICAVA®

The following video shows how to properly prepare and administer RADICAVA®. If you have been prescribed RADICAVA®, it may be helpful to share this guide with the care team member who is assisting with your infusions.


Preparing for Your Infusion

Receiving RADICAVA® outside the home

If you receive RADICAVA® (edaravone) at an infusion center, hospital, or doctor's office, you will typically go through a few steps. These may vary depending on your location.

Preparing for your infusion Step 1

Check in and meet with a nurse or infusion technician who will be giving you your medication.

Preparing for your infusion Step 2

Your nurse or technician will confirm your name, the medicine name (RADICAVA®), and your dosage.

Preparing for your infusion Step 3

Your vital signs will be checked.

Preparing for your infusion Step 4

An IV line will be inserted in your vein or a port, if you have one.

Preparing for your infusion Step 5

Two 30 mg IV bags will be infused (60 mg total). It takes about 60 minutes to receive a full dose of RADICAVA®.

Preparing for your infusion Step 6

After your infusion, the IV line will be removed.

You should be able to continue with your normal routine after your infusion.

Your HCP will monitor you during treatment to watch for signs and symptoms of all serious side effects. Call your HCP if you experience any side effects.

Tell your HCP right away or go to the nearest emergency room if you have any of the following symptoms: hives; swelling of the lips, tongue, or face; fainting; breathing problems; wheezing; trouble swallowing; dizziness; itching; or an asthma attack (in people with asthma).

Here are a few things you may want to consider on your infusion days.
  • There are no eating restrictions. Feel free to eat before or have a snack on hand
  • Dress comfortably. It's recommended that you wear relaxed, loose-fitting clothing
  • It's okay to drink liquids. Staying hydrated may make it easier to find a vein
  • Ask questions. Medical professionals are available to help
  • Keep yourself entertained. Read a book or magazine, use your cell phone for games, text, music, etc

The information and advice provided here are general in nature and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. You are strongly encouraged to seek the advice of your doctor or other qualified healthcare provider with any questions regarding a medical condition.

Reference: 1. Data on file. Mitsubishi Tanabe Pharma America, Inc.

Important Safety Information

Before you receive Radicava® (edaravone), tell your healthcare provider about all of your medical conditions, including if you:

  • have asthma.
  • are allergic to other medicines.
  • are pregnant or plan to become pregnant. It is not known if Radicava® will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Radicava® passes into your breastmilk. You and your healthcare provider should decide if you will receive Radicava® or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Radicava®?

  • Radicava® may cause serious side effects, including hypersensitivity (allergic) reactions and sulfite allergic reactions.
  • Hypersensitivity reactions have happened in people receiving Radicava® and can happen after your infusion is finished.
  • Radicava® contains sodium bisulfite, a sulfite that may cause a type of allergic reaction that can be serious and life-threatening. Sodium bisulfite can also cause less severe asthma episodes in certain people. Sulfite sensitivity can happen more often in people who have asthma than in people who do not have asthma.
  • Tell your healthcare provider right away or go to the nearest emergency room if you have any of the following symptoms: hives; swelling of the lips, tongue, or face; fainting; breathing problems; wheezing; trouble swallowing; dizziness; itching; or an asthma attack (in people with asthma).
  • Your healthcare provider will monitor you during treatment to watch for signs and symptoms of all the serious side effects.

The most common side effects of Radicava® include bruising (contusion), problems walking (gait disturbance), and headache.

These are not all the possible side effects of Radicava®. Call your healthcare provider for medical advice about side effects. You may report side effects to Mitsubishi Tanabe Pharma America, Inc. at 1-888-292-0058 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Indication

Radicava® is indicated for the treatment of amyotrophic lateral sclerosis (ALS).

Please see full Prescribing Information and Patient Information.

For more information about RADICAVA®, call 1-844-SRCHLGT ( 1-844-772-4548).