RADICAVA ORS® is a MAJOR CONTRIBUTION TO PATIENT CARE Call a JourneyMate Resource Specialist at 1-855-457-6968.
RADICAVA ORS® is a MAJOR CONTRIBUTION TO PATIENT CARE Call a JourneyMate Resource Specialist at 1-855-457-6968.
Get answers about starting RADICAVA ORS® (edaravone) and how the JourneyMate Support Program™ can help you.
Have questions about starting treatment?
Call a JourneyMate Resource Specialist at 1-855-457-6968 between 9 AM and 9 PM ET, Monday through Friday.
Learn more
Q: How many people have used RADICAVA ORS® and how many doctors have prescribed it?
17,300+ people have been treated with RADICAVA ORS® since 2022 for 1.9 million+ days of therapy.a,b
1600+ doctors in the US have prescribed RADICAVA ORS®.a
aBased on RADICAVA ORS® prescriptions submitted in the US as of May 2026. Not independently verified.
bDays of therapy based on number of Starter Kit and Maintenance Kit cartons sold for RADICAVA ORS® as of May 2026. Each Starter Kit includes 14 days of therapy, and each Maintenance Kit includes 10 days of therapy.
Q: Why was RADICAVA ORS® recognized in 2024 for its major contribution to patient care?
RADICAVA ORS® provides a clinically superior option for patients due to its oral suspension route of administration. RADICAVA ORS® provides a less burdensome option vs the intravenous administration.c (see footnote)
Q: How can I get help accessing RADICAVA ORS®?
Once your doctor has prescribed RADICAVA ORS® and submitted a Benefit Investigation and Enrollment Form (BIF) to check how your health insurance covers RADICAVA ORS®, an Insurance & Access Specialist will reach out to help you understand the insurance process.
An Insurance & Access Specialist will:
Help to investigate your health insurance coverage and health plan benefits, as well as the RADICAVA ORS® financial support options which may be available to you
Answer your questions and let you know what is needed next at each step in the process as you pursue treatment
Help you understand how to access your RADICAVA ORS® medication from a specialty pharmacy
Learn how the JourneyMate Support Program™ can help you with checking insurance coverage and understanding support resources. Watch the How to Get Started With RADICAVA ORS® video.
Q: How do I enroll in the JourneyMate Support Program™?
To be enrolled in the JourneyMate Support Program™, your doctor must submit a completed and signed Benefit Investigation and Enrollment Form (BIF), which includes a prescription for RADICAVA ORS®, to the JourneyMate Support Program™. You will also need to authorize your enrollment in the program. You may do so by signing the BIF or the Patient Authorization Form.
If you're unable to provide your signature on the form—for whatever reason—a JourneyMate Support Program™ Insurance & Access Specialist will contact you to obtain your authorization.
Q: Can I get help paying for RADICAVA ORS®?
The JourneyMate Support Program™ Insurance & Access Specialist can give you information about financial support options and other sources of financial assistance that may be available to you if you meet all eligibility criteria.
If you meet the eligibility requirements and are otherwise eligible for treatment with RADICAVA ORS®, you may be enrolled when your healthcare provider submits a Benefit Investigation and Enrollment Form for RADICAVA ORS®, which you have signed. If you are in financial need and have no insurance, you may qualify for the Patient Assistance Program.
For questions about financial support options, call the JourneyMate Support Program™ Insurance & Access Specialist at 1-844-772-4548.
Q: What can I do if my insurance company denies coverage for RADICAVA ORS®?
Your insurance company may initially deny your treatment with RADICAVA ORS®. If this happens, you may be able to do something about it. Here are some ideas you may find helpful:
Talk to your doctor to see if it may be possible to file an appeal
If your request for an exception is denied you may be able to appeal the decision.
Having your doctor file an appeal may help give your insurance provider more details about why you should receive treatment.
If the appeal does not work, your doctor may request a next-level appeal. Some of the people that may be involved include a panel of doctors, an administrative judge, or a local state representative.
Consider other insurance plan options
If you or or your loved one has been diagnosed with ALS, there may be government health plan options to consider. Regardless of age, people diagnosed with ALS can apply for Social Security Disability Insurance (SSDI) benefits, and subsequently, can apply for Medicare and/or Medicaid coverage.
For questions about appeals or insurance coverage, call the JourneyMate Support Program™ Insurance & Access Specialist at 1-844-772-4548 to learn more.
Q: What is the re-enrollment process for the Out-of-Pocket Savings Program?
You will be re-enrolled and remain in the Out-of-Pocket Savings Program in 2026 so long as reverification of your insurance benefits confirms that you continue to meet the eligibility requirements for participation in the Out-of-Pocket Savings Program. You will receive a letter notifying you of this information at the end of each calendar year.
Please be sure to notify the JourneyMate Support Program™ Insurance & Access Specialist at any time during the 2026 calendar year if you have any change in your status, which affects your ability to meet the eligibility requirements for the Out-of-Pocket Savings Program. If you are no longer eligible, you will be unable to continue participation in the Out-of-Pocket Savings Program, and your personalized information will no longer be active for out-of-pocket assistance.
cUS Food and Drug Administration. Clinical superiority findings https://www.fda.gov/industry/designating-orphan-product-drugs-and-biological-products/clinical-superiority-findings. Return to content
Do not receive RADICAVA ORS® (edaravone) if you are allergic to edaravone or any of the ingredients in RADICAVA ORS.
Before you take RADICAVA ORS, tell your healthcare provider about all of your medical conditions, including if you:
have asthma.
are allergic to other medicines.
are pregnant or plan to become pregnant. It is not known if RADICAVA ORS will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if RADICAVA ORS passes into your breastmilk. You and your healthcare provider should decide if you will receive RADICAVA ORS or breastfeed.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of RADICAVA ORS?
RADICAVA ORS may cause serious side effects, including hypersensitivity (allergic) reactions and sulfite allergic reactions.
Hypersensitivity reactions have happened in people taking RADICAVA ORS and can happen after your medicine has been taken.
RADICAVA ORS contains sodium bisulfite, a sulfite that may cause a type of allergic reaction that can be serious and life-threatening. Sodium bisulfite can also cause less severe asthma episodes in certain people. Sulfite sensitivity can happen more often in people who have asthma than in people who do not have asthma.
Tell your healthcare provider right away or go to the nearest emergency room if you have any of the following symptoms: hives; swelling of the lips, tongue, or face; fainting; breathing problems; wheezing; trouble swallowing; dizziness; itching; or an asthma attack (in people with asthma).
Your healthcare provider will monitor you during treatment to watch for signs and symptoms of all the serious side effects and allergic reactions.
Common side effects reported include bruising (contusion), problems walking (gait disturbance), headache and fatigue. These are not all the possible side effects of RADICAVA ORS.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch or Shionogi Inc. at 1-888-292-0058.
INDICATION
RADICAVA ORS® (edaravone) is indicated for the treatment of amyotrophic lateral sclerosis (ALS).
Please see the full Prescribing Information and Patient Information, also available at www.radicavaors.com.
Do not receive RADICAVA ORS® (edaravone) if you are allergic to edaravone or any of the ingredients in RADICAVA ORS.
Before you take RADICAVA ORS, tell your healthcare provider about all of your medical conditions, including if you:
have asthma.
are allergic to other medicines.
are pregnant or plan to become pregnant. It is not known if RADICAVA ORS will harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if RADICAVA ORS passes into your breastmilk. You and your healthcare provider should decide if you will receive RADICAVA ORS or breastfeed.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of RADICAVA ORS?
RADICAVA ORS may cause serious side effects, including hypersensitivity (allergic) reactions and sulfite allergic reactions.
Hypersensitivity reactions have happened in people taking RADICAVA ORS and can happen after your medicine has been taken.
RADICAVA ORS contains sodium bisulfite, a sulfite that may cause a type of allergic reaction that can be serious and life-threatening. Sodium bisulfite can also cause less severe asthma episodes in certain people. Sulfite sensitivity can happen more often in people who have asthma than in people who do not have asthma.
Tell your healthcare provider right away or go to the nearest emergency room if you have any of the following symptoms: hives; swelling of the lips, tongue, or face; fainting; breathing problems; wheezing; trouble swallowing; dizziness; itching; or an asthma attack (in people with asthma).
Your healthcare provider will monitor you during treatment to watch for signs and symptoms of all the serious side effects and allergic reactions.
Common side effects reported include bruising (contusion), problems walking (gait disturbance), headache and fatigue. These are not all the possible side effects of RADICAVA ORS.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to www.fda.gov/medwatch or Shionogi Inc. at 1-888-292-0058.
INDICATION
RADICAVA ORS® (edaravone) is indicated for the treatment of amyotrophic lateral sclerosis (ALS).
Please see the full Prescribing Information and Patient Information, also available at www.radicavaors.com.
© 2026 Shionogi Inc. Florham Park, NJ 07932. All Rights Reserved.
RADICAVA, RADICAVA ORS, and the RADICAVA ORS logo are registered trademarks of Shionogi Inc.
JourneyMate Support Program is a trademark of Shionogi Inc.
All other trademarks are the property of their respective owners.
Intended for US Residents Only.
CP-OE-US-1717 07/26
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